It targets the cochlea in the inner ear Scientists have developed a new approach to repair cells
deep inside the ear, a potential remedy that could restore hearing for millions
of elderly people and others who suffer hearing loss.
A study, published in the journal Bioconjugate
Chemistry , demonstrated a novel way for a drug to zero in on damaged
nerves and cells inside the ear. The research was conducted on animal tissues in a petri
dish. The drug targets the cochlea, a snail-like structure in the inner ear
where sensitive cells convey sound to the brain, according to the researchers
from University of Southern California in the U.S.Hearing loss can occur due to various reasons like ageing,
noisy machines and too many loud concerts.
Over time, hair-like sensory cells and bundles
of neurons that transmit their vibrations break down, as do ribbon-like
synapses, which connect the cells. The researchers designed a molecule
combining 7,8-dihydroxyflavone, which mimics a protein critical for development
and function of the nervous system, and bisphosphonate, a type of drug that
sticks to bones.
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